Factors associated with poor fetal outcome in placental abruption

We aimed at describing placental abruption in our county and evaluating factors associated with poor fetal outcome. In this case-control study, women were identified from two databases of Brest University Hospital between January 2013 December 2018. Placental histological findings, course pregnancies, maternal characteristics described compared cases (placental stillbirth or neonatal death) controls. 135 abruption, whom 24.4% complicated 6.5% death. Forty percent smokers 14.1% had a history vasculoplacental disorder. Pregnancies 42.2% pre-eclampsia 43% intrauterine growth restriction. Cases more autoimmune diseases mother (20.0% versus 3.2%, P = 0.003), aspirin heparin use during pregnancy 6.3%, 0.03), less (25.0% 49.5%, 0.01) deliveries ≤ 34 weeks gestation (80.0% 43.2%, 0.0001) than Placentas showed indentation ≥ 30% (42.5% 5.3%, < chronic inflammation, especially chorioamniotitis (2.5% 24.2%, 0.002) multivariate analysis, negatively outcome inflammation (P macroscopic infarcts 0.01). Poor is certain lesions, but not pre-eclampsia, what suggests various pathophysiological processes among abruption.